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Sumatera utara
INDONESIA
Buletin Farmatera
Published by Universitas Muhammadiyah Sumatera Utara
ISSN : 2528410X     EISSN : 2528410X     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Arjuna Subject : -
Articles 10 Documents
 1 
Search results for , issue "Vol 8, No 1 (2023)" : 10 Documents clear
The Safety Evaluation of Some Plants of the Zingibereceae Family Doni Anshar Nuari; Asman Sadino; Suci Hilwa Ainaya
Buletin Farmatera Vol 8, No 1 (2023)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v8i1.11478

Abstract

Overview of Ivabradine Drug: Use and History Melviana Lubis
Buletin Farmatera Vol 8, No 1 (2023)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v8i1.12751

Abstract

Despite the significant advances in management and prevention, heart failure still cause high mortality and morbidity. Ivabradine is one example of a new drug used in the treatment of heart failure with decreased ejection fraction. Ivabradine history and use is interesting that it can improve our understanding to cardiovascular pathophysiology. There may also be extended indications for Ivabradine use in the future.
Analysis of Breast Care Factors for Increasing Breast Milk Production In Pagar Merbau Public Health Community Center, Medan Zaim Anshari
Buletin Farmatera Vol 8, No 1 (2023)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v8i1.5522

Abstract

Breastfeeding is the obligation of a mother to give milk to her baby after childbirth (post-partum). To provide the right quantity and quality of breast milk that requires a formal agreement, such as maintaining and caring for breasts. Breast care should start from the time of pregnancy during childbirth (puerperium). Several factors that need to consider in breast care are providing breast massage, maintaining breast hygiene, using a bra as a breast protector, and consuming nutrition. This study is a quasi-experimental study that aims to determine whether breast care can increase milk production in post-partum mothers. The results showed that offering massage to the breasts, maintaining breast hygiene, and consuming nutrition affected the production of breast milk in post-partum mothers. The use of a bra in post-partum mothers does not have a significant effect on increasing milk production in post-partum mothers.
The Correlation of Body Mass Index with Visceral and Subcutaneous Adipose Tissue Volume in Patients that Performed Abdominal CT scan at RSUP H. Adam Malik Medan Duma Ratna Sari Nasution; Netty Delvrita Lubis; Naomi Niari Dalimunthe
Buletin Farmatera Vol 8, No 1 (2023)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v8i1.12656

Abstract

Visceral and subcutaneous adipose tissue (VAT and SAT), and excess body mass index (BMI) act as cardiometabolic risk factors. BMI only describes the ratio of body weight to height in general. Abdominal CT scan is the gold standard in the examination of VAT and SAT volumes. The purpose of this study is to analyze the correlation between BMI with VAT and SAT in patients that performed CT scans of the abdomen. A total of 60 patients who underwent CT scans of the abdominal region at the Radiology Department of the RSUP H. Adam Malik Medan from July to August 2022 participated in this cross-sectional study. The BMI was calculated from measurement and volume of VAT and SAT were obtained from CT scans of the abdominal region at the fourth lumbal level, using 3D smart segmentation. Among of samples was 51.7% male. Average of age and BMI are 49.3 12.18 years and 25.58 kg/m2. Average of VAT and SAT volume value are 678.13 436.09 cm3 and 1708.76 1068.99 cm3. There is a moderate positive correlation between BMI and VAT (r=0.687) and BMI and SAT (r=0.669) with p0.001.
Yield Analysis and Phytochemical Screening of Ethanol Extract of Phaleria macrocarpa Leaves Ira Cinta Lestari; Dharma Lindarto; Syafruddin Ilyas; Tri Widyawati; Suryani Eka Mustika
Buletin Farmatera Vol 8, No 1 (2023)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v8i1.11724

Abstract

Phaleria macrocarpa leaves have the potential to be used as raw materials for medicines derived from natural ingredients, but research is needed to determine the content and efficacy of these plants. This study aims to analyze the yield and screening of the content of phytochemical compounds in the ethanolic extract of the Phaleria macrocarpa leaves. This research is a descriptive study. Extract yield analysis was performed by calculating the weight ratio of the extract divided by the simplicia multiplied by one hundred percent. Screening for the phytochemical content was carried out for compounds belonging to the class of flavonoids, saponins, tannins, alkaloids, steroids, and triterpenoids. The results of the calculation of the yield of the extract obtained were 14.58% and the results of the phytochemical test showed that the extract contained flavonoids, alkaloids, tannins, glycosides, saponins, and steroids.
Malnutrition Screening Is Better Than Body Mass Index for Predicting COVID-19 Severity Fitri Nur Malini Siregar; Asri Ludin Tambunan; Eka Febriyanti
Buletin Farmatera Vol 8, No 1 (2023)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v8i1.11619

Abstract

Abstract: Several factors can influence the severity of COVID-19, including nutritional status and malnutrition conditions. This study compares malnutrition screening methods with body mass index to find better predictors of COVID-19 severity. This study is a cross-sectional analysis of medical records from all adult COVID-19 patients (total sampling) treated at Amri Tambunan Deli Serdang Hospital. The World Health Organization criteria were used to determine the severity of COVID-19. A Global Subjective Assessment (SGA) questionnaire was used to screen for malnutrition, while anthropometric measurements (Kg/m2) were used to calculate the Body Mass Index (BMI). The Chi-Square Test was used for statistical analysis. This study included 508 COVID-19 hospitalisation patients, the majority of whom were women (55.5%), aged 18-29 years (25%) and had moderate severity (89.6%). The seriousness of COVID-19 was associated with malnutrition conditions as measured by the SGA questionnaire (p0.001), with patients with moderate to severe malnutrition being 3.4 times more likely to develop robust and critical COVID-19 (95% CI 1.6 - 7.0). There is no significant relationship between Body Mass Index and the severity of COVID-19 (p0.05). Malnutrition screening with SGA is more accurate than BMI in predicting the severity of COVID-19. Keywords:   IMT, a predictor of COVID-19 severity degree, malnutrition screening 
Microscopic Features of Central Caseous Necrosis in Tuberculosis Lymphadenitis Patients: The Relationship with Lymphocyte Density Rafa Nabila Haifa; Humairah Medina Liza Lubis
Buletin Farmatera Vol 8, No 1 (2023)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v8i1.12282

Abstract

Tuberculosis lymphadenitis (TBLN) is the most common extra pulmonary TB (EPTB) case in the world with a range of 30-40% of all EPTB cases. When the body's immune system cannot kill the pathogen, the body will try to contain the pathogen (granuloma). The outer portion of the granuloma becomes calcified and the cells in the center undergo necrosis. The formation of central necrosis is associated with the emergence of cellular hypersensitivity with the features of local accumulation of macrophages and lymphocytes. The current study aimed to determine the relationship between the microscopic features of central caseous necrosis with lymphocyte density in patients with tuberculous lymphadenitis. Thirty histopathological slides of TBLN patients were observed under a microscope to see the features of central caseous necrosis and assess the lymphocyte density with the results assessed based on the cutoff point of the median of all lymphocyte mean values. Based on the microscopic examination, 25 samples of central caseous necrosis were found and the other 5 samples were not found to have caseous necrosis. Twenty-six patients had low lymphocyte density, and 4 patients had high lymphocyte density. The results of the Fisher Exact test obtained p = 0.009. There is a significant relationship between the features of central caseous necrosis and lymphocyte density in patients with TBLN.
Prevalence and Profile of Patients with Otitis Externa at the Universitas Sumatera Utara Hospital in Medan in 2020-2021 Qatrunnada Medina Salim; Adlin Adnan; Indri Adriztina; Iman Dwi Winanto
Buletin Farmatera Vol 8, No 1 (2023)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v8i1.13101

Abstract

Otitis externa is an acute or chronic inflammation of the ear canal which also involves the tympanic membrane and pinna. This disease has a prevalence rate of about 10% of all ENT diseases. Aim. This research aims to determine the prevalence and profile of the disease based on demographic characteristics (age, sex, and occupation), chief complaint, type, location, and comorbidities in patients with otitis externa. Methods. This research is a hospital-based retrospective study of patients diagnosed with otitis externa in Universitas Sumatera Utara Hospital Medan for the period January 2020 to December 2021. Data were obtained from medical records then processed using the SPSS program and analyzed using descriptive statistics. Results. The total number of patients in Universitas Sumatera Utara Hospital for the 2020-2021 period who met the study inclusion and exclusion criteria was 291 patients. Found 47.4% male and 52.6% female with a ratio of 1:1.1. The peak age group at 26-45 years was 36.8%. In employment status, 23.0% are self-employed and patients who do not work 22.7% are the majority while 0.3% POLRI of and laborers are a minority. The majority 72.5% come with a chief complaint of pain or tenderness in the ear followed by 10% of the ear that felt full. The most common type of otitis externa was acute diffuse as much as 91.8% with the location of the right ear that was most often complained of as much as 44.7%. Otitis externa disease is commonly found in patients who do not have other comorbidities as much as 87.3%. Conclusion. Otitis externa is a common ear disease that affects all age groups and genders. Most of the patients come with complaints of pain in the right ear and were diagnosed with acute diffuse otitis externa.
Association of Intestinal Parasite Infection and Environmental Sanitation Marusaha Selamet Wijaya; Lambok Siahaan; Inke Nadia
Buletin Farmatera Vol 8, No 1 (2023)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v8i1.11060

Abstract

Abstract: Intestinal parasitic infection is a problem that is still widely encountered in health-related communities with a fairly high morbidity rate of 411 per 1,000 population in Indonesia and 12.5% in the city of Medan. The cause is due to protozoan infection and to helminthiasis. Transmission of parasitic infections has risk factors that greatly influence, namely personal hygiene, residence, access to health education, family education, shoe wearing habits, hand washing practices, toilet availability, availability of clean water and defecation practices. This study was conducted to determine the relationship between intestinal parasitic infections and environmental sanitation at Helvetia Health Center, Labuan Health Center, Martubung Health Center. Analytical conservation (Chi-Square) with cross-sectional design. At least 100 people met the inclusion criteria. Data from surveys are results obtained over time from survey respondents' responses and information from survey participants' stool samples examined under a microscope using lugol and diethyl ether. From a total of 100 samples, it was found that 8 (8%) people suffered from intestinal parasitic infections with Trichuris trichiura 1 (1%), Hookworm 3 (3%), and Blastocystis 4  (4%). There were 100 (100%) samples that had good sanitation. No significant association was found between intestinal parasitic infection and environmental sanitation in the study sample (p = 0.08). There is no relationship between intestinal parasitic infections and environmental sanitation.
Evaluation Of The Quality Of Packed Red Cell (PRC) In the Blood Donation Unit (BDU) Of The Indonesian Red Cross (IRC) Of Banda Aceh City: Haemolysis Rate As An Indicator Of A Good Quality Control Process Teuku Ilhami Surya Akbar; Wizar Putri Mellaratna; Ratna Sari Dewi; Evanulia Evanulia
Buletin Farmatera Vol 8, No 1 (2023)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v8i1.12168

Abstract

Abstract: PRC is the most commonly used component of blood. This blood component comes from whole blood which then goes through a centrifugation process to separate into PRC blood components. In this separation process, it is not uncommon to cause haemolysis, which in the end PRC blood products do not provide a therapeutic effect for recipients. This study will look at the percentage of haemolysis that occurs during separation and whether it is still up to standard. This study aims to determine the risk of haemolysis in the processing of PRC blood products stored for 30 days at BDU of IRC of Banda Aceh City. Research benefits are knowing the risk of haemolysis in the processing of PRC blood products stored for 30 days at BDU IRC Banda Aceh City. This study used the cross-sectional method. The samples in this study amounted to 95 donor blood samples taken from blood bags with a shelf life of 30 days. Techniques sample sampling using a total sampling technique. Samples will be examined quantitatively with a value of the percentage of haemolysis of the blood sample. The samples test will be seen whether haemolysis occurs (0.8%) or not/non-haemolysis (0.8%) automatically using the HemoCue Plasma/Low tool. Of the 95 samples tested, 7.3% (7) of the samples were haemolyzed and 92.8% (88) samples did not have haemolysis. This study showed that the majority of samples did not have haemolysis with a percentage of 92.8% and those with haemolysis were only 7.3%. This shows that the quality of blood services at BDU of IRC of Banda Aceh City is still by Peraturan Menteri Kesehatan (PMK) or regulation of the minister of health standard No. 91 yr. 2015 with the percentage of samples that do not undergo haemolysis above 75%. 

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